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Article

The [4Fe-4S] cluster of quinolinate synthase from Escherichia coli: investigation of cluster ligands.

FEBS letters - 20 Aug 2008

Rousset Carine, Fontecave Marc, Ollagnier de Choudens Sandrine

Abstract excerpt

Nicotinamide adenine dinucleotide (NAD) derives from quinolinic acid which is synthesized in Escherichia coli from l-aspartate and dihydroxyacetone phosphate through the concerted action of l-aspartate oxidase and the [4Fe-4S] quinolinate synthase (NadA). Here, we addressed the question of the identity of the cluster ligands. We performed in vivo complementation experiments as well as enzymatic, spectroscopic and...

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Identifiers

PMID: 18674537
DOI: 10.1016/j.febslet.2008.07.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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