Article
Molecular surveillance of Neisseria meningitidis capsular switching in Portugal, 2002-2006.
Epidemiology and infection - 1 Feb 2009
Simões M J, Cunha M, Almeida F, Furtado C, Brum L
Abstract excerpt
Neisseria meningitidis capsular switching has been reported in several countries. In order to establish the genetic relationship within group B and C strains expressing subtypes 2a or 2b, and to evaluate whether C to B capsular switching occurred in Portugal, 64 meningococci (56 serogroup C and 8 serogroup B) isolated from invasive meningococcal disease were typed using molecular methods. The studied phenotypes,...
Topics
- Antigenic Variation
- Bacterial Capsules
- Bacterial Typing Techniques
- Cluster Analysis
- DNA Fingerprinting
- DNA, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Genotype
- Humans
- Meningococcal Infections
- Neisseria meningitidis
- Portugal
- Sequence Analysis, DNA
- Serotyping
