Article
Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection.
The New England journal of medicine - 6 Aug 2009
McHutchison John G, Lawitz Eric J, Shiffman Mitchell L, Muir Andrew J, Galler Greg W, McCone Jonathan, Nyberg Lisa M, Lee William M, Ghalib Reem H, Schiff Eugene R, Galati Joseph S, Bacon Bruce R, Davis Mitchell N, Mukhopadhyay Pabak, Koury Kenneth, Noviello Stephanie, Pedicone Lisa D, Brass Clifford A, Albrecht Janice K, Sulkowski Mark S
Abstract excerpt
BACKGROUND: Treatment guidelines recommend the use of peginterferon alfa-2b or peginterferon alfa-2a in combination with ribavirin for chronic hepatitis C virus (HCV) infection. However, these regimens have not been adequately compared. METHODS: At 118 sites, patients who had HCV genotype 1 infection and who had not previously been treated were randomly assigned to undergo 48 weeks of treatment with one of three...
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