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Article

Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery

24 Jul 2008

Abstract excerpt

BACKGROUND: Strategies to discover circulating protein markers of ovarian cancer are urgently needed. We developed a novel technology that permits us to isolate recombinant antibodies directed against the potential serum biomarkers, to facilitate the further development of affinity reagents necessary to construct diagnostic tests. METHODS: This study presents a novel discovery approach based on serum...

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PMID: 18652693
DOI: 10.1186/1479-5876-6-41

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