Article
Polymorphisms in the vascular endothelial growth factor gene and the risk of familial endometriosis.
Molecular human reproduction - 1 Sept 2008
Zhao Zhen Zhen, Nyholt Dale R, Thomas Shane, Treloar Susan A, Montgomery Grant W
Abstract excerpt
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific angiogenic protein suspected to be involved in the pathogenesis of endometriosis by establishing a new blood supply to the human exfoliated endometrium. Several transcription factor-binding sites are found in the VEGF 5'-untranslated region and variation within the region increases the transcriptional activity. Six previous studies which...
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