Determination of genetic variation within Plasmodium falciparum by using enzymatically amplified DNA from filter paper disks impregnated with whole blood.

doi:10.1128/jcm.29.6.1171-1174.1991

Back to search

Article

Determination of genetic variation within Plasmodium falciparum by using enzymatically amplified DNA from filter paper disks impregnated with whole blood.

Journal of clinical microbiology - 1 Jun 1991

Kain K C, Lanar D E

Abstract excerpt

A new method which allows the enzymatic amplification of DNA extracted from whole blood dried on filter paper disks is presented. The method was used to study heterogeneity within an erythrocyte-binding antigen (EBA-175) of Plasmodium falciparum. Blood specimens from malaria-infected patients in...

Topics

Animals
Antigens, Protozoan
Base Sequence
DNA, Protozoan
Filtration
Gene Amplification
Genetic Variation
Humans
Malaria
Molecular Sequence Data
Plasmodium falciparum
Polymerase Chain Reaction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.