Article
A new regulatory circuit in ribosomal protein operons: S2-mediated control of the rpsB-tsf expression in vivo.
RNA (New York, N.Y.) - 1 Sept 2008
Aseev Leonid V, Levandovskaya Alexandrina A, Tchufistova Ludmila S, Scaptsova Nadezda V, Boni Irina V
Abstract excerpt
Autogenous regulation is a general strategy of balancing ribosomal protein synthesis in bacteria. Control mechanisms have been studied in detail for most of ribosomal protein operons, except for rpsB-tsf encoding essential r-protein S2 and elongation factor Ts, where even the promoter has remained unknown. By using single-copy translational fusions with the chromosomal lacZ gene and Western-blot analysis, we...
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