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Article

Crystal structures of Drosophila mutant translin and characterization of translin variants reveal the structural plasticity of translin proteins.

The FEBS journal - 1 Aug 2008

Gupta Gagan D, Makde Ravindra D, Rao Basuthkar J, Kumar Vinay

Abstract excerpt

Translin protein is highly conserved in eukaryotes. Human translin binds both ssDNA and RNA. Its nucleic acid binding site results from a combination of basic regions in the octameric structure. We report here the first biochemical characterization of wild-type Drosophila melanogaster (drosophila) translin and a chimeric translin, and present 3.5 A resolution crystal structures of drosophila P168S mutant translin...

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Identifiers

PMID: 18647346
DOI: 10.1111/j.1742-4658.2008.06571.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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