Article
SLC26A4 c.919-2A>G varies among Chinese ethnic groups as a cause of hearing loss.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Aug 2008
Dai Pu, Li Qi, Huang Deliang, Yuan Yongyi, Kang Dongyang, Miller David T, Shao Hong, Zhu Qingwen, He Jia, Yu Fei, Liu Xin, Han Bing, Yuan Huijun, Platt Orah S, Han Dongyi, Wu Bai-Lin
Abstract excerpt
PURPOSE: Mutations in the SLC26A4 gene are second only to GJB2 mutations as a currently identifiable genetic cause of sensorineural hearing loss. In most areas of China, genetic testing for sensorineural hearing loss is unavailable because of limited knowledge of the mutation spectrum. Although SLC26A4 c.919-2A>G (IVS7-2A>G) is a common mutation among some Asian populations, the mutation prevalence among various...
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