Article
Comparison of the Mutation Spectrum of Common Deafness-Causing Genes in 509 Patients With Nonsyndromic Hearing Loss in 4 Different Areas of China by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.
The journal of international advanced otology - 1 Nov 2021
Wang Yi, Chen Wencheng, Liu Zhizhong, Xing Wen, Zhang Haiyan
Abstract excerpt
BACKGROUND: The aim of this study is to compare the spectrum and frequency of GJB2, SLC26A4, GJB3, and MT-RNR1 mutations in 4 different areas of China. METHODS: A total of 509 patients from Linyi, Xinxiang, Yichang, and Baise were enrolled in this study. Twenty of the most common mutation sites were analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. RESULTS: Patients from...
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