Article
Molecular characterization of the porcine JHDM1A gene associated with average daily gain: evaluation its role in skeletal muscle development and growth.
Molecular biology reports - 1 Oct 2011
Peng Yong-Bo, Fan Bin, Han Xue-Lei, Xu Xue-Wen, Rothschild Max F, Yerle Martine, Liu Bang
Abstract excerpt
JHDM1A, a member of the JHDM (JmjC-domain-containing histone demethylase) family, plays an central role in gene silencing, cell cycle, cell growth and cancer development through histone H3K36 demethylation modification. Here reported the cloning, expression, chromosomal location and association analysis with growth traits of porcine JHDM1A gene. Sequence analysis showed that the porcine JHDM1A gene encodes 1,162...
Topics
- Animals
- Breeding
- Chromosome Mapping
- Conserved Sequence
- Fetus
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Gene Frequency
- Genetic Linkage
- Genotype
- Least-Squares Analysis
- Muscle Development
- Muscle, Skeletal