Article
The altered expression of syndecan 4 in the uninvolved skin of venous leg ulcer patients may predispose to venous leg ulcer.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1 Jan 2000
Nagy Nikoletta, Németh István Balázs, Szabad Gábor, Szolnoky Gyõzõ, Belsõ Nóra, Bata-Csörgõ Zsuzsanna, Dobozy Attila, Kemény Lajos, Széll Márta
Abstract excerpt
Syndecan 4 (SDC4), a heparan sulfate proteoglycan, and neuropilin 1 (NRP1), a transmembrane receptor, are both involved in normal wound healing, but little is known about their possible role in venous leg ulcer pathogenesis. We aimed to investigate whether there are any expression abnormalities and/or gene polymorphisms of SDC4 and NRP1 associated with venous leg ulcer. SDC4 showed significantly lower mRNA and...
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