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Article

Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects.

The Journal of infectious diseases - 15 Sept 2008

Bartels Doug J, Zhou Yi, Zhang Eileen Z, Marcial Michelle, Byrn Randal A, Pfeiffer Thomas, Tigges Ann M, Adiwijaya Bambang S, Lin Chao, Kwong Ann D, Kieffer Tara L

Abstract excerpt

BACKGROUND: The prevalence and clinical implications of naturally occurring variants that are resistant to hepatitis C virus (HCV) protease inhibitors in treatment-naive patients has not been reported. We report here the prevalence of such variants and their effect on clinical response. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18637752
DOI: 10.1086/591141

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18637752-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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