Article
A226V mutation in virus during the 2007 chikungunya outbreak in Kerala, India.
The Journal of general virology - 1 Aug 2008
Kumar N Pradeep, Joseph Rajan, Kamaraj T, Jambulingam P
Abstract excerpt
Kerala State in India was gripped by a renewed and widespread outbreak of Chikungunya virus (CHIKV) infection during 2007. Here, we report the A226V mutation in the glycoprotein envelope 1 (E1) gene of the virus among isolates collected from the three worst-affected districts of the state during this outbreak. This mutation had already been suggested to be directly responsible for a significant increase in CHIKV...
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