Article
The Lon protease regulates swarming motility and virulence gene expression in Proteus mirabilis.
Journal of medical microbiology - 1 Aug 2008
Clemmer Katy M, Rather Philip N
Abstract excerpt
A mini-Tn5lacZ1 transposon insertion in a gene encoding an orthologue of the Lon protease conferred a hyper-swarming phenotype on Proteus mirabilis. The lon mutation increased the accumulation of mRNA for representative class 1 (flhDC), class 2 (fliA) and class 3 (flaA) genes during swarmer cell differentiation. In addition, the stability of the FlhD protein was fourfold higher in the lon : mini-Tn5lacZ1...
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