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Article

Molecular mechanisms of rotational catalysis in the F(0)F(1) ATP synthase.

Biochimica et biophysica acta - 31 May 2000

Nakamoto R K, Ketchum C J, Kuo P H, Peskova Y B, Al-Shawi M K

Abstract excerpt

Rotation of the F(0)F(1) ATP synthase gamma subunit drives each of the three catalytic sites through their reaction pathways. The enzyme completes three cycles and synthesizes or hydrolyzes three ATP for each 360 degrees rotation of the gamma subunit. Mutagenesis studies have yielded considerable information on the roles of interactions between the rotor gamma subunit and the catalytic beta subunits. Amino acid...

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PMID: 10838045
DOI: 10.1016/s0005-2728(00)00081-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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