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An Insect Virus-Encoded MicroRNA Regulates Viral Replication

10 Jul 2008

Abstract excerpt

MicroRNAs (miRNAs) are small ( approximately 22 nucleotides) noncoding RNAs which play an essential role in gene regulation and affect a wide range of processes, including development, differentiation, and oncogenesis. Here we report the identification of the first miRNA from an insect virus, derived from the major capsid protein (MCP) gene in Heliothis virescens ascovirus (HvAV) (HvAV-miR-1). Although MCP was...

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PMID: 18614632
DOI: 10.1128/jvi.01109-08

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