Article
[Targeted therapy for locally advanced and/or metastatic bladder cancer].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie - 1 Jul 2008
Wallerand H, Robert G, Bernhard J-C, Ravaud A, Ferrière J-M
Abstract excerpt
Cancer is a complex disease characterized by a multitude of molecular and genetic abnormalities affecting cell proliferation and differentiation, apoptosis, and mobility (invasion). Each of these alterations represents a potential target for the development of targeted therapy. These new therapies inhibit cell growth and are said to be "cytostatic" in contrast with conventional "cytotoxic" chemotherapy. As a...
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