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Article

IMP dehydrogenase-linked retinitis pigmentosa.

Nucleosides, nucleotides & nucleic acids - 1 Jun 2008

Hedstrom Lizbeth

Abstract excerpt

Many retinal diseases are caused by mutations in photoreceptor-specific proteins. However, retinal disease can also result from mutations in widely expressed proteins. One such protein is inosine monophosphate dehydrogenase type 1 (IMPDH1), which catalyzes a key step in guanine nucleotide biosynt...

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Source

Identifiers

PMID: 18600550
DOI: 10.1080/15257770802146486

Genes

IMPDH1
CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18600550-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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IMP dehydrogenase-linked retinitis pigmentosa.PMID 18600550Read ↗

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Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding.Semantic proximity Read ↗

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On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosaSemantic proximity Read ↗

Why Do Mutations in the Ubiquitously Expressed Housekeeping Gene<i>IMPDH1</i>Cause Retina-Specific Photoreceptor Degeneration?Semantic proximity Read ↗

Molecular mechanisms of photoreceptor degeneration in RP caused by IMPDH1 mutations.Semantic proximity Read ↗

Investigating the mechanism of disease in the RP10 form of retinitis pigmentosa.Semantic proximity Read ↗

IMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNA.Semantic proximity Read ↗

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On the role of IMPDH1 in retinal degeneration.Semantic proximity Read ↗

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