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Article

Human Cytomegalovirus Infection Alters the Expression of Cellular MicroRNA Species That Affect Its Replication

3 Jul 2008

Abstract excerpt

The human genome encodes over 500 microRNAs (miRNAs), small RNAs (19 to 26 nucleotides [nt]) that regulate the expressions of diverse cellular genes. Many cellular processes are altered through a variety of mechanisms by human cytomegalovirus (HCMV) infection. We asked whether HCMV infection leads to changes in the expression of cellular miRNAs and whether HCMV-regulated miRNAs are important for HCMV replication....

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PMID: 18596100
DOI: 10.1128/jvi.00961-08

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