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Article

Transient dimerization and interaction with ERGIC-53 occur in the fibroblast growth factor receptor 3 early secretory pathway.

The international journal of biochemistry & cell biology - 1 Jan 2008

Lievens Patricia M-J, De Servi Barbara, Garofalo Silvio, Lunstrum Gregory P, Horton William A, Liboi Elio

Abstract excerpt

The fibroblast growth factor receptor 3 (FGFR3) secretory pathway includes N-linked glycosylation in the endoplasmic reticulum where a stringent quality control system ensures that only correctly folded receptor reaches the cell surface from where mature-functional FGFR3 signals upon ligand-mediated dimerization. We have previously shown that the increased kinase activity associated with FGFR3 bearing the...

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Source

Identifiers

PMID: 18577465
DOI: 10.1016/j.biocel.2008.05.017

Genes

FGFR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Transient dimerization and interaction with ERGIC-53 occur in the fibroblast growth factor receptor 3 early secretory pathway.PMID 18577465Read ↗

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