Article
The Gln/Gln genotype of XPD codon 751 as a genetic marker for melanoma risk and Lys/Gln as an important predictor for melanoma progression: a case control study in the Swedish population.
Oncology reports - 1 Jul 2008
Kertat Khadija, Rosdahl Inger, Sun Xiao-Feng, Synnerstad Ingrid, Zhang Hong
Abstract excerpt
The Xeroderma pigmentosum complementation group D (XPD) is a critical protein in the nucleotide excision repair system for DNA damage. Genetic variations in XPD exert an important effect on the capacity of DNA repair. In this study, we examined Lys751Gln polymorphism at the XPD gene in 244 melanoma patients and 251 healthy individuals (as controls) from the south-eastern region of Sweden. The associations of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.