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Article

Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2008

Libé Rossella, Fratticci Amato, Coste Joel, Tissier Frédérique, Horvath Anelia, Ragazzon Bruno, Rene-Corail Fernande, Groussin Lionel, Bertagna Xavier, Raffin-Sanson Marie Laure, Stratakis Constantine A, Bertherat Jérome

Abstract excerpt

PURPOSE: We have reported previously nonsense inactivating mutations of the phosphodiesterase 11A (PDE11A) gene in patients with micronodular adrenocortical hyperplasia and Cushing syndrome. The aim of this study is to investigate the presence of somatic or germ-line PDE11A mutations in various types of adrenocortical tumors: ACTH-independent macronodular adrenocortical hyperplasia (AIMAH), adrenocortical adenoma...

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Identifiers

PMID: 18559625
DOI: 10.1158/1078-0432.CCR-08-0106
PMCID: PMC3134879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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