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Article

Valproate teratogenicity and epilepsy syndrome

13 Jun 2008

Abstract excerpt

Maternal valproate (VPA) use is associated with a significant risk for congenital malformations in the exposed fetus. Since VPA is commonly used in epilepsy syndromes with a presumed genetic cause (idiopathic epilepsies), it is possible that maternal genetic background contributes to this outcome. We reviewed responses to telephone questionnaires and medical records, when available, of enrollees in the North...

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PMID: 18557775
DOI: 10.1111/j.1528-1167.2008.01696.x

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