Article
Cross-species infection of specific-pathogen-free pigs by a genotype 4 strain of human hepatitis E virus.
Journal of medical virology - 1 Aug 2008
Feagins A R, Opriessnig T, Huang Y W, Halbur P G, Meng X J
Abstract excerpt
Hepatitis E virus (HEV) is an important pathogen. The animal strain of HEV, swine HEV, is related to human HEV. The genotype 3 swine HEV can infect humans and genotype 3 human HEV can infect pigs. The genotype 4 swine and human HEV strains are genetically related, but it is unknown whether genotype 4 human HEV can infect pigs. A swine bioassay was utilized in this study to determine whether genotype 4 human HEV...
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