Article
AMYPdb: A database dedicated to amyloid precursor proteins
10 Jun 2008
Abstract excerpt
BACKGROUND: Misfolding and aggregation of proteins into ordered fibrillar structures is associated with a number of severe pathologies, including Alzheimer's disease, prion diseases, and type II diabetes. The rapid accumulation of knowledge about the sequences and structures of these proteins allows using of in silico methods to investigate the molecular mechanisms of their abnormal conformational changes and...
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