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Article

Mutation Analysis of the PINK1 Gene in 391 Patients With Parkinson Disease

1 Jun 2008

Abstract excerpt

OBJECTIVES: To determine the frequency, distribution, and clinical features of Parkinson disease (PD) with PINK1 mutations. DESIGN: Retrospective clinical and genetic review. SETTING: University hospital. PATIENTS: We performed extensive mutation analyses of PINK1 in 414 PD patients negative for parkin mutations (mean [SD] age at onset, 42.8 [14.3] years), including 391 unrelated patients (190 patients with...

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PMID: 18541801
DOI: 10.1001/archneur.65.6.802

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