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Article

Impact of luxS and suppressor mutations on the gastrointestinal transit of Lactobacillus rhamnosus GG.

Applied and environmental microbiology - 1 Aug 2008

Lebeer Sarah, Claes Ingmar J J, Verhoeven Tine L A, Shen Chong, Lambrichts Ivo, Ceuppens Jan L, Vanderleyden Jos, De Keersmaecker Sigrid C J

Abstract excerpt

It is generally believed that probiotic bacteria need to survive gastrointestinal transit to exert a health-promoting effect. In this study, a genuine luxS mutant and a luxS mutant containing unknown suppressor mutations of the probiotic strain Lactobacillus rhamnosus GG were compared to the wild type for survival and persistence in the murine gastrointestinal tract. The LuxS enzyme, catalyzing the production of...

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Identifiers

PMID: 18539797
DOI: 10.1128/AEM.00133-08
PMCID: PMC2519330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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