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Cytopathogenicity and molecular subtyping of Legionella pneumophila environmental isolates from 17 hospitals.

Epidemiology and infection - 1 Feb 2009

Garcia-Nuñez M, Pedro-Botet M L, Ragull S, Sopena N, Morera J, Rey-Joly C, Sabria M

Abstract excerpt

The cytopathogenicity of 22 Legionella pneumophila isolates from 17 hospitals was determined by assessing the dose of bacteria necessary to produce 50% cytopathic effect (CPED50) in U937 human-derived macrophages. All isolates were able to infect and grow in macrophage-like cells (range log10 CPED50: 2.67-6.73 c.f.u./ml). Five groups were established and related to the serogroup, the number of PFGE patterns...

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Identifiers

PMID: 18538055
DOI: 10.1017/S0950268808000691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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