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Article

Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity.

Molecular cancer - 5 Jun 2008

Combaret Valérie, Boyault Sandrine, Iacono Isabelle, Brejon Stéphanie, Rousseau Raphaël, Puisieux Alain

Abstract excerpt

BACKGROUND: Bortezomib, a specific and selective inhibitor of the 26S proteasome with antitumor activity against a wide range of malignancies, has been approved for the treatment of relapsed or refractory multiple myeloma and other cancers. Recently, bortezomib has been identified as an effective inhibitor of neuroblastoma cell growth and angiogenesis. RESULTS: In the present study, we demonstrate that some...

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Identifiers

PMID: 18534018
DOI: 10.1186/1476-4598-7-50
PMCID: PMC2442611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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