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Article

Treatment modality affects allograft-derived Schwann cell phenotype and myelinating capacity.

Experimental neurology - 1 Aug 2008

Hayashi Ayato, Moradzadeh Arash, Tong Alice, Wei Cindy, Tuffaha Sami H, Hunter Daniel A, Tung Thomas H, Parsadanian Alexander, Mackinnon Susan E, Myckatyn Terence M

Abstract excerpt

We used peripheral nerve allografts, already employed clinically to reconstruct devastating peripheral nerve injuries, to study Schwann cell (SC) plasticity in adult mice. By modulating the allograft treatment modality we were able to study migratory, denervated, rejecting, and reinnervated phenotypes in transgenic mice whose SCs expressed GFP under regulatory elements of either the S100b (S100-GFP) or nestin...

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Identifiers

PMID: 18514192
DOI: 10.1016/j.expneurol.2008.04.018
PMCID: PMC2806227

Genes

CFP
MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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