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Article

amnesiac regulates sleep onset and maintenance in Drosophila melanogaster.

Biochemical and biophysical research communications - 8 Aug 2008

Liu Weijie, Guo Fang, Lu Beika, Guo Aike

Abstract excerpt

The adenylate cyclase/cAMP signaling pathway and adult mushroom bodies (MBs) have been shown to play an important role in sleep regulation in Drosophila. The amnesiac (amn) gene, encodes a neuropeptide that is homologous with vertebrate pituitary adenylate cyclase-activating peptide (PACAP), is expressed in dorsal paired medial (DPM) neurons and is required for the middle-term memory (MTM) in flies. However, the...

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PMID: 18514063
DOI: 10.1016/j.bbrc.2008.05.119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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