Article
The transmembrane isoform of Plasmodium falciparum MAEBL is essential for the invasion of Anopheles salivary glands.
PloS one - 28 May 2008
Saenz Fabian E, Balu Bharath, Smith Jonah, Mendonca Sarita R, Adams John H
Abstract excerpt
Malaria transmission depends on infective stages in the mosquito salivary glands. Plasmodium sporozoites that mature in midgut oocysts must traverse the hemocoel and invade the mosquito salivary glands in a process thought to be mediated by parasite ligands. MAEBL, a homologue of the transmembrane EBP ligands essential in merozoite invasion, is expressed abundantly in midgut sporozoites. Alternative splicing...
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