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Article

MAEBL Is Essential for Malarial Sporozoite Infection of the Mosquito Salivary Gland

20 May 2002

Abstract excerpt

Malarial sporozoites mature in the oocysts formed in the mosquito midgut wall and then selectively invade the salivary glands, where they wait to be transmitted to the vertebrate host via mosquito bite. Invasion into the salivary gland has been thought to be mediated by specific ligand-receptor interactions, but the molecules involved in these interactions remain unknown. MAEBL is a single transmembrane-like...

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PMID: 12021311
DOI: 10.1084/jem.20011876

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