Article
Inactivation of the cystatin E/M tumor suppressor gene in cervical cancer.
Genes, chromosomes & cancer - 1 Sept 2008
Veena Mysore S, Lee Grant, Keppler Daniel, Mendonca Marc S, Redpath J Leslie, Stanbridge Eric J, Wilczynski Sharon P, Srivatsan Eri S
Abstract excerpt
We have previously localized a cervical cancer tumor suppressor gene to a 300 kb interval of 11q13. Analysis of candidate genes revealed loss of expression of cystatin E/M, a lysosomal cysteine protease inhibitor, in 6 cervical cancer cell lines and 9 of 11 primary cervical tumors. Examination of...
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