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Article

Functional genomics and SNP analysis of human genes encoding proline metabolic enzymes.

Amino acids - 1 Nov 2008

Hu Chien-An A, Bart Williams D, Zhaorigetu Siqin, Khalil Shadi, Wan Guanghua, Valle David

Abstract excerpt

Proline metabolism in mammals involves two other amino acids, glutamate and ornithine, and five enzymatic activities, Delta(1)-pyrroline-5-carboxylate (P5C) reductase (P5CR), proline oxidase, P5C dehydrogenase, P5C synthase and ornithine-delta-aminotransferase (OAT). With the exception of OAT, which catalyzes a reversible reaction, the other four enzymes are unidirectional, suggesting that proline metabolism is...

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Identifiers

PMID: 18506409
DOI: 10.1007/s00726-008-0107-9
PMCID: PMC2707926

Genes

OAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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