Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

1 May 2008

Abstract excerpt

MicroRNAs are small noncoding RNAs that have critical roles in regulating a number of cellular functions through transcriptional silencing. They have been implicated as oncogenes and tumor suppressor genes (oncomirs) in several human neoplasms. We used an integrated genomics and functional screening strategy to identify potential oncomirs in the pediatric neoplasm neuroblastoma. We first identified microRNAs that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Remodeling and Cancer
Share to Neuroblastoma Research and Treatments
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18505919
DOI: 10.1158/1541-7786.mcr-07-2102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor GenePMID 18505919Read ↗

MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cellsSemantic proximity Read ↗

Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastomaSemantic proximity Read ↗

MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastomaSemantic proximity Read ↗

Early Targets of miR-34a in NeuroblastomaSemantic proximity Read ↗

MicroRNA-542-5p as a novel tumor suppressor in neuroblastomaSemantic proximity Read ↗

MicroRNA Involvement in the Pathogenesis of Neuroblastoma: Potential for MicroRNA Mediated TherapeuticsSemantic proximity Read ↗

miR-34a inhibits progression of neuroblastoma by targeting autophagy-related gene 5Semantic proximity Read ↗

MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma.Semantic proximity Read ↗

MiR-34a deficiency accelerates medulloblastoma formation in vivo.Semantic proximity Read ↗

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiationSemantic proximity Read ↗

Differential Patterns of MicroRNA Expression in Neuroblastoma Are Correlated with Prognosis, Differentiation, and ApoptosisSemantic proximity Read ↗

microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrestSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.