Molecular analyses of an acidic transthyretin Asn 90 variant.

Article

Molecular analyses of an acidic transthyretin Asn 90 variant.

American journal of human genetics - 1 May 1991

Saraiva M J, Almeida M R, Alves I L, Moreira P, Gawinowicz M, Costa P P, Rauh S, Banhzoff A, Altland K

Abstract excerpt

A mutation in transthyretin (TTR Asn 90) has been identified in the Portuguese and German populations. This variant has a lower pI and was found by screening analyses in 2/4,000 German subjects and in 4/1,200 Portuguese by using either double one-dimensional (D1-D) electrophoresis with isoelectri...

Topics

Adult
Amyloidosis
Female
Germany
Heterozygote
Humans
Male
Mutation
Pedigree
Peripheral Nervous System Diseases
Portugal
Prealbumin

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