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Article

Properties of plasmids responsible for production of extended-spectrum beta-lactamases.

Antimicrobial agents and chemotherapy - 1 Jan 1991

Jacoby G A, Sutton L

Abstract excerpt

The extended-spectrum beta-lactamases are believed to arise by mutations which alter the configuration around the active site of TEM- and SHV-type enzymes so as to increase their efficiency with otherwise nonhydrolyzable cephalosporins and monobactams. This hypothesis predicts that the genes for these new enzymes should be found on the same wide variety of plasmids that encode TEM-1, TEM-2, and SHV-1...

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Identifiers

PMID: 1849707
DOI: 10.1128/AAC.35.1.164
PMCID: PMC244959

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Source receipt: pubmed, retrieved 7 Sept 2026.

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