Properties of plasmids responsible for production of extended-spectrum beta-lactamases.

doi:10.1128/AAC.35.1.164

Back to search

Article

Properties of plasmids responsible for production of extended-spectrum beta-lactamases.

Antimicrobial agents and chemotherapy - 1 Jan 1991

Jacoby G A, Sutton L

Abstract excerpt

The extended-spectrum beta-lactamases are believed to arise by mutations which alter the configuration around the active site of TEM- and SHV-type enzymes so as to increase their efficiency with otherwise nonhydrolyzable cephalosporins and monobactams. This hypothesis predicts that the genes for...

Topics

DNA Transposable Elements
Mutation
Plasmids
beta-Lactamases

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.