Article
Modularity of stress response evolution.
Proceedings of the National Academy of Sciences of the United States of America - 27 May 2008
Singh Amoolya H, Wolf Denise M, Wang Peggy, Arkin Adam P
Abstract excerpt
Responses to extracellular stress directly confer survival fitness by means of complex regulatory networks. Despite their complexity, the networks must be evolvable because of changing ecological and environmental pressures. Although the regulatory networks underlying stress responses are characterized extensively, their mechanism of evolution remains poorly understood. Here, we examine the evolution of three...
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