Article
Effect of aeration and agitation on the protease production by Staphylococcus aureus mutant RC128 in a stirred tank bioreactor.
Bioprocess and biosystems engineering - 1 Jan 2009
Ducros E, Ferrari M, Pellegrino M, Raspanti C, Bogni C
Abstract excerpt
The modified rotating simplex method has been successfully used to determine the best combination of agitation rate and aeration rate for maximum production of extracellular proteases by Staphylococcus aureus mutant RC128, in a stirred tank bioreactor operated in a discontinuous way. This mutant has shown altered exoprotein production, specially enhanced protease production. Maximum production of proteases (15.28...
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