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Article

Regulated import and degradation of a cytosolic protein in the yeast vacuole.

Nature - 28 Mar 1991

Chiang H L, Schekman R

Abstract excerpt

The key regulatory enzyme in gluconeogenesis, fructose 1,6-bisphosphatase (FBPase) is subject to glucose-stimulated proteolytic degradation in Saccharomyces cerevisiae. This process involves the regulated transfer of FBPase directly from the cytosol into the vacuole or a vacuole-related organelle. Glucose may regulate the production of an FBPase receptor or import factor that is transported to the vacuole through...

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PMID: 1848921
DOI: 10.1038/350313a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Regulated import and degradation of a cytosolic protein in the yeast vacuole.PMID 1848921Read ↗

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