Regulated import and degradation of a cytosolic protein in the yeast vacuole.

doi:10.1038/350313a0

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Article

Regulated import and degradation of a cytosolic protein in the yeast vacuole.

Nature - 28 Mar 1991

Chiang H L, Schekman R

Abstract excerpt

The key regulatory enzyme in gluconeogenesis, fructose 1,6-bisphosphatase (FBPase) is subject to glucose-stimulated proteolytic degradation in Saccharomyces cerevisiae. This process involves the regulated transfer of FBPase directly from the cytosol into the vacuole or a vacuole-related organelle...

Topics

Cytosol
Endopeptidases
Fructose-Bisphosphatase
Kinetics
Models, Biological
Molecular Weight
Mutation
Saccharomyces cerevisiae
Vacuoles

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