Article
Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa.
PLoS pathogens - 16 May 2008
Mendes Antonio M, Schlegelmilch Timm, Cohuet Anna, Awono-Ambene Parfait, De Iorio Maria, Fontenille Didier, Morlais Isabelle, Christophides George K, Kafatos Fotis C, Vlachou Dina
Abstract excerpt
In much of sub-Saharan Africa, the mosquito Anopheles gambiae is the main vector of the major human malaria parasite, Plasmodium falciparum. Convenient laboratory studies have identified mosquito genes that affect positively or negatively the developmental cycle of the model rodent parasite, P. berghei. Here, we use transcription profiling and reverse genetics to explore whether five disparate mosquito gene...
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