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Article

Use of sirolimus in IPEX and IPEX-like children.

Journal of clinical immunology - 1 Sept 2008

Yong Pierre L, Russo Pierre, Sullivan Kathleen E

Abstract excerpt

INTRODUCTION: IPEX (immune dysregulation, polyendocrinopathy, enteropathy, and X-linked syndrome), a rare inflammatory disease caused by mutations of Foxp3, destroys the immunoregulatory environment of affected male infants. Data on optimal therapy are limited. METHODS: We reviewed the effect of sirolimus use in our cohort of IPEX and IPEX-like patients (n = 7). RESULTS AND DISCUSSION: Our patients exhibited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18481161
DOI: 10.1007/s10875-008-9196-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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