Article
Validation of a composite score for clinical severity of hemophilia.
Journal of thrombosis and haemostasis : JTH - 1 Jul 2008
Schulman S, Eelde A, Holmström M, Ståhlberg G, Odeberg J, Blombäck M
Abstract excerpt
INTRODUCTION: Evaluation of modulators of the phenotypic expression of hemophilia may benefit from a scoring system that reflects several aspects of the clinical severity instead of only one dimension. METHODS: We describe here how we constructed a composite Hemophilia Severity Score (HSS) and performed validation. The items in the HSS are annual incidence of joint bleeds, World Federation of Hemophilia...
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