Article
Rat liver polysome N alpha-acetyltransferase: substrate specificity.
Biochemistry - 29 Jan 1991
Yamada R, Bradshaw R A
Abstract excerpt
The substrate specificity of polysome rat liver N alpha-acetyltransferase (NAT) has been examined by utilizing a series of synthetic and natural substrates that has been systematically altered with respect to N-terminal sequence and length. Families of peptides of the structure S-Y-S-G-G-L-L-L were generated by successively replacing the N-terminal serine, the penultimate tyrosine, and the antepenultimate serine...
Topics
- Acetylation
- Acetyltransferases
- Adrenocorticotropic Hormone
- Amino Acid Sequence
- Animals
- Molecular Sequence Data
- Mutation
- N-Terminal Acetyltransferases
- Polyribosomes
- Protein Biosynthesis
- Rats
- Substrate Specificity
