Article
Herpes simplex virus (HSV) glycoprotein H is partially processed in a cell line that expresses the glycoprotein and fully processed in cells infected with deletion or ts mutants in the known HSV glycoproteins.
Virology - 1 Feb 1991
Foà-Tomasi L, Avitabile E, Boscaro A, Brandimarti R, Gualandri R, Manservigi R, Dall'Olio F, Serafini-Cessi F, Fiume G C
Abstract excerpt
Cell lines that constitutively express herpes simplex virus 1 (HSV-1) glycoprotein H (gH-1) failed to synthesize the mature form of gH and accumulated a precursor-like form of the glycoprotein, which was retained intracellularly, most likely in RER. Fine-structure analysis of the oligosaccharides...
Topics
- Animals
- Cell Line
- Chromosome Deletion
- Genes, Viral
- Mannose
- Mutation
- Oligosaccharides
- Plasmids
- Protein Processing, Post-Translational
- Recombinant Proteins
- Recombination, Genetic
- Restriction Mapping
- Simplexvirus