Article
Epidemiologic patterns of wild-type hepatitis A virus determined by genetic variation.
The Journal of infectious diseases - 1 Feb 1991
Robertson B H, Khanna B, Nainan O V, Margolis H S
Abstract excerpt
Hepatitis A virus (HAV) isolates from different parts of the world are a single serotype. However, genetic analysis of the VP1 genome region of published HAV sequences suggested that distinct genotypes of HAV could be defined based upon the geographic source of the original isolates. To circumvent the process of cell culture adaptation or animal passage, a 247-bp segment within the VP1 genome region of wild-type...
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