Article
Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications.
Proceedings of the National Academy of Sciences of the United States of America - 13 May 2008
Tong Zongzhong, Yang Zhenglin, Patel Shrena, Chen Haoyu, Gibbs Daniel, Yang Xian, Hau Vincent S, Kaminoh Yuuki, Harmon Jennifer, Pearson Erik, Buehler Jeanette, Chen Yuhong, Yu Baifeng, Tinkham Nicholas H, Zabriskie Norman A, Zeng Jiexi, Luo Ling, Sun Jennifer K, Prakash Manvi, Hamam Rola N, Tonna Stephen, Constantine Ryan, Ronquillo Cecinio C, Sadda SriniVas, Avery Robert L, Brand John M, London Nyall, Anduze Alfred L, King George L, Bernstein Paul S, Watkins Scott, Jorde Lynn B, Li Dean Y, Aiello Lloyd Paul, Pollak Martin R, Zhang Kang
Abstract excerpt
Significant morbidity and mortality among patients with diabetes mellitus result largely from a greatly increased incidence of microvascular complications. Proliferative diabetic retinopathy (PDR) and end stage renal disease (ESRD) are two of the most common and severe microvascular complications of diabetes. A high concordance exists in the development of PDR and ESRD in diabetic patients, as well as strong...
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