Article
1,4GlcNAc-capped mucin-type O-glycan inhibits cholesterol -glucosyltransferase from Helicobacter pylori and suppresses H. pylori growth
9 Apr 2008
Abstract excerpt
Helicobacter pylori infects over half of the world's population and is thought to be a leading cause of gastric ulcer, gastric carcinoma, and gastric malignant lymphoma of mucosa-associated lymphoid tissue type. Previously, we reported that a gland mucin (MUC6) present in the lower portion of the gastric mucosa containing alpha1,4-N-acetylglucosamine (alpha1,4GlcNAc)-capped core 2-branched O-glycans suppresses H....
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